Efficacy of linezolid alone or in combination with vancomycin for treatment of experimental endocarditis due to methicillin-resistant Staphylococcus aureus

被引：51

作者：

Chiang, FY

Climo, M

机构：

[1] Hunter Holmes McGuire Vet Affairs Med Ctr, Richmond, VA 23249 USA

[2] Virginia Commonwealth Univ Hlth Syst, Div Infect Dis, Richmond, VA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 09期

关键词：

D O I：

10.1128/AAC.47.9.3002-3004.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The levels of effectiveness of linezolid, vancomycin, and the combination of linezolid and vancomycin were compared in the rabbit model of endocarditis caused by a clinical methicillin-resistant Staphylococcus aureus (MRSA) isolate. Vancomycin alone was more effective than either linezolid alone or the combination of linezolid and vancomycin for the treatment of endocarditis due to MRSA.

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收藏

页码：3002 / 3004

页数：3

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