Emergence of NDM-1-Producing Enterobacteriaceae in Belgium

被引：55

作者：

Bogaerts, Pierre ^{[1
]}

Bouchahrouf, Warda ^{[1
]}

de Castro, Roberta Rezende ^{[1
]}

Deplano, Ariane ^{[2
]}

Berhin, Catherine ^{[1
]}

Pierard, Denis ^{[3
]}

Denis, Olivier ^{[2
]}

Glupczynski, Youri ^{[1
]}

机构：

[1] Clin Univ UCL Mt Godinne, Bacteriol Lab, B-5530 Yvoir, Belgium

[2] Hop Univ ULB Erasme, Bacteriol Lab, Brussels, Belgium

[3] Univ Ziekenhuis Brussel, Lab Clin Microbiol, Brussels, Belgium

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 06期

关键词：

METALLO-BETA-LACTAMASE; ESCHERICHIA-COLI; CTX-M; RESISTANCE; MICROARRAY; GENES; SHV; TEM;

D O I：

10.1128/AAC.00049-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-beta-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum beta-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes (qnrA6, qnrB1, qnrB2). One patient died from uncontrolled sepsis, while the two others recovered. No secondary cases occurred in any of the hospitals.

引用

页码：3036 / 3038

页数：3

共 17 条

[1] Nosocomial infections caused by multidrug-resistant Pseudomonas putida isolates producing VIM-2 and VIM-4 metallo-β-lactamases [J].

Bogaerts, Pierre ;

Huang, Te-Din ;

Rodriguez-Villalobos, Hector ;

Bauraing, Caroline ;

Deplano, Ariane ;

Struelens, Marc J. ;

Glupczynski, Youri .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (03) :749-751

[2]

Bogaerts P, 2010, LANCET INFECT DIS, V10, P831, DOI 10.1016/S1473-3099(10)70278-4

[3] Identification of plasmids by PCR-based replicon typing [J].

Carattoli, A ;

Bertini, A ;

Villa, L ;

Falbo, V ;

Hopkins, KL ;

Threlfall, EJ .

JOURNAL OF MICROBIOLOGICAL METHODS, 2005, 63 (03) :219-228

[4]

Clinical and Laboratory Standards Institute, 2010, CLSI M100S20

[5] Evaluation of a Commercial Microarray System for Detection of SHV-, TEM-, CTX-M-, and KPC-Type β-Lactamase Genes in Gram-Negative Isolates [J].

Endimiani, Andrea ;

Hujer, Andrea M. ;

Hujer, Kristine M. ;

Gatta, Julian A. ;

Schriver, Andrew C. ;

Jacobs, Michael R. ;

Rice, Louis B. ;

Bonomo, Robert A. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (07) :2618-2622

[6]

Hammerum AM, 2010, LANCET INFECT DIS, V10, P829, DOI 10.1016/S1473-3099(10)70276-0

[7] Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study [J].

Kumarasamy, Karthikeyan K. ;

Toleman, Mark A. ;

Walsh, Timothy R. ;

Bagaria, Jay ;

Butt, Fafhana ;

Balakrishnan, Ravikumar ;

Chaudhary, Uma ;

Doumith, Michel ;

Giske, Christian G. ;

Irfan, Seema ;

Krishnan, Padma ;

Kumar, Anil V. ;

Maharjan, Sunil ;

Mushtaq, Shazad ;

Noorie, Tabassum ;

Paterson, David L. ;

Pearson, Andrew ;

Perry, Claire ;

Pike, Rachel ;

Rao, Bhargavi ;

Ray, Ujjwayini ;

Sarma, Jayanta B. ;

Sharma, Madhu ;

Sheridan, Elizabeth ;

Thirunarayan, Mandayam A. ;

Turton, Jane ;

Upadhyay, Supriya ;

Warner, Marina ;

Welfare, William ;

Livermore, David M. ;

Woodford, Neil .

LANCET INFECTIOUS DISEASES, 2010, 10 (09) :597-602

[8] Evaluation of a DNA Microarray, the Check-Points ESBL/KPC Array, for Rapid Detection of TEM, SHV, and CTX-M Extended-Spectrum β-Lactamases and KPC Carbapenemases [J].

Naas, T. ;

Cuzon, G. ;

Truong, H. ;

Bernabeu, S. ;

Nordmann, P. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2010, 54 (08) :3086-3092

[9] How To Detect NDM-1 Producers [J].

Nordmann, Patrice ;

Poirel, Laurent ;

Carrer, Amelie ;

Toleman, Mark A. ;

Walsh, Timothy R. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (02) :718-721

[10] Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR [J].

Pérez-Pérez, FJ ;

Hanson, ND .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (06) :2153-2162

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