Possible central nervous system infection by SARS coronavirus

被引：281

作者：

Lau, KK ^{[1
]}

Yu, WC

Chu, CM

Lau, ST

Sheng, B

Yuen, KY

机构：

[1] Princess Margaret Hosp, Dept Med & Geriatr, Kwai Chung, Hong Kong, Peoples R China

[2] United Christian Hosp, Kwun Tong, Hong Kong, Peoples R China

[3] Univ Hong Kong, Queen Marys Hosp, Hong Kong, Hong Kong, Peoples R China

来源：

EMERGING INFECTIOUS DISEASES | 2004年 / 10卷 / 02期

关键词：

D O I：

10.3201/eid1002.030638

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

On day 22 of illness, generalized tonic-clonic convulsion developed in a 32-year-old woman with severe acute respiratory syndrome (SARS). Cerebrospinal fluid tested positive for SARS coronavirus (SARS-CoV) by reverse transcriptase-polymerase chain reaction. SARS-CoV may have caused an infection in the central nervous system in this patient.

引用

页码：342 / 344

页数：3

共 12 条

[1]

Arbour N, 1998, ADV EXP MED BIOL, V440, P575

[2] Neuroinvasion by human respiratory coronaviruses [J].

Arbour, N ;

Day, R ;

Newcombe, J ;

Talbot, PJ .

JOURNAL OF VIROLOGY, 2000, 74 (19) :8913-8921

[3]

Blau DM, 2001, ADV EXP MED BIOL, V494, P193

[4] Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area [J].

Booth, CM ;

Matukas, LM ;

Tomlinson, GA ;

Rachlis, AR ;

Rose, DB ;

Dwosh, HA ;

Walmsley, SL ;

Mazzulli, T ;

Avendano, M ;

Derkach, P ;

Ephtimios, IE ;

Kitai, I ;

Mederski, BD ;

Shadowitz, SB ;

Gold, WL ;

Hawryluck, LA ;

Rea, E ;

Chenkin, JS ;

Cescon, DW ;

Poutanen, SM ;

Detsky, AS .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (21) :2801-2809

[5] Hypomagnesemic disorders [J].

Dacey, MJ .

CRITICAL CARE CLINICS, 2001, 17 (01) :155-+

[6]

KROLL MH, 1985, CLIN CHEM, V31, P244

[7] A major outbreak of severe acute respiratory syndrome in Hong Kong [J].

Lee, N ;

Hui, D ;

Wu, A ;

Chan, P ;

Cameron, P ;

Joynt, GM ;

Ahuja, A ;

Yung, MY ;

Leung, CB ;

To, KF ;

Lui, SF ;

Szeto, CC ;

Chung, S ;

Sung, JJY .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (20) :1986-1994

[8] HUMAN CORONAVIRUSES - A BRIEF REVIEW [J].

MYINT, SH .

REVIEWS IN MEDICAL VIROLOGY, 1994, 4 (01) :35-46

[9] Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study [J].

Peiris, JSM ;

Chu, CM ;

Cheng, VCC ;

Chan, KS ;

Hung, IFN ;

Poon, LLM ;

Law, KI ;

Tang, BSF ;

Hon, TYW ;

Chan, CS ;

Chan, KH ;

Ng, JSC ;

Zheng, BJ ;

Ng, WL ;

Lai, RWM ;

Guan, Y ;

Yuen, KY .

LANCET, 2003, 361 (9371) :1767-1772

[10] ANTIBODIES TO CORONAVIRUSES OC43 AND 229E IN MULTIPLE-SCLEROSIS PATIENTS [J].

SALMI, A ;

ZIOLA, B ;

HOVI, T ;

REUNANEN, M .

NEUROLOGY, 1982, 32 (03) :292-295

← 1 2 →