Hexabromocyclododecane in marine species from the Western Scheldt Estuary:: Diastereoisomer- and enantiomer-specific accumulation

被引:230
作者
Janák, K
Covaci, A
Voorspoels, S
Becher, G
机构
[1] Norwegian Inst Publ Hlth, Div Environm Med, NO-0403 Oslo, Norway
[2] Univ Antwerp, Toxicol Ctr, B-2610 Antwerp, Belgium
关键词
D O I
10.1021/es0484909
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Hexabromocyclododecane (HBCD) is a widely used brominated flame retardant, which is increasingly reported in the environment. Here, we report on the diastereomeric and, for the first time, on the enantiomeric composition of HBCD in muscle and liver of several fish species caught in the Western Scheldt Estuary (The Netherlands). The total HBCD content (sum of (9 alpha-, beta-, and gamma-diastereoisomers), as well as the distribution of diastereoisomers and enantiomers, varied between the species. The levels of total HBCD (9-1110 ng/g lipid weight) found in fish tissues were higher than those measured in fish from European rivers with no known point sources of HBCD but lower than in fish samples collected near factories producing or using HBCD. The concentrations of total HBCD expressed on a lipid weight basis were higher in liver than in muscle for bib and whiting, while in sole, HBCD had no preferential distribution between the tissues. A similar pattern for liver and muscle distribution was already observed for polybrominated diphenyl ethers (PBDEs) in these species. The (alpha-HBCD diastereoisomer was most abundant in all fish samples with a higher contribution to the total HBCD levels in liver compared to muscle for bib and whiting. The gamma-HBCD diastereoisomer accumulated less in liver than in muscle of sole, bib, and whiting. For the first time, enantiomer fractions were determined for HBCD diastereoisomers in liver of three fish species and in muscle of two fish species. A significant enrichment of the (+) alpha-HBCD enantiomer was found in whiting and bib liver samples. A high enantioselectivity has also been seen for the gamma-HBCD diastereoisomer in whiting liver.
引用
收藏
页码:1987 / 1994
页数:8
相关论文
共 32 条
[1]  
Allchin C., 2003, ORGANOHALOGEN COMPD, V61, P41
[2]   Thermal stability and decomposition products of hexabromocyclododecane [J].
Barontini, F ;
Cozzani, V ;
Petarca, L .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2001, 40 (15) :3270-3280
[3]   The stereochemistry of 1,2,5,6,9,10-hexabromocyclododecane and its graphic representation [J].
Becher, G .
CHEMOSPHERE, 2005, 58 (07) :989-991
[4]   Congener-specific analysis of hexabromocyclododecane by high-performance liquid chromatography/electrospray tandem mass spectrometry [J].
Budakowski, W ;
Tomy, G .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2003, 17 (13) :1399-1404
[5]   Determination of brominated flame retardants, with emphasis on polybrominated diphenyl ethers (PBDEs) in environmental and human samples - a review [J].
Covaci, A ;
Voorspoels, S ;
de Boer, J .
ENVIRONMENT INTERNATIONAL, 2003, 29 (06) :735-756
[6]   Developments in the use of chromatographic techniques in marine laboratories for the determination of halogenated contaminants and polycyclic aromatic hydrocarbons [J].
de Boer, J ;
Law, RJ .
JOURNAL OF CHROMATOGRAPHY A, 2003, 1000 (1-2) :223-251
[7]   Enantiomer fractions instead of enantiomer ratios [J].
de Geus, HJ ;
Wester, PG ;
de Boer, J ;
Brinkman, UAT .
CHEMOSPHERE, 2000, 41 (05) :725-727
[8]   An overview of brominated flame retardants in the environment [J].
de Wit, CA .
CHEMOSPHERE, 2002, 46 (05) :583-624
[9]  
DEBOER J, 2002, HBCD TBBP SEWAGE SLU
[10]   Occurrence and bioavailability of polybrominated diphenyl ethers and hexabromocyclododecane in sediment and fish from the Cinca River, a tributary of the Ebro River (Spain) [J].
Eljarrat, E ;
De La Cal, A ;
Raldua, D ;
Duran, C ;
Barcelo, D .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2004, 38 (09) :2603-2608