Control of Pseudomonas aeruginosa algZ expression by the alternative sigma factor AlgT

被引:36
作者
Wozniak, DJ [1 ]
Sprinkle, AB [1 ]
Baynham, PJ [1 ]
机构
[1] Wake Forest Univ, Sch Med, Dept Microbiol & Immunol, Winston Salem, NC 27157 USA
关键词
D O I
10.1128/JB.185.24.7297-7300.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
AlgZ controls Pseudomonas aeruginosa alginate synthesis by activating algD, yet algZ expression is not detectable in nonmucoid strains. Mobility shift and Western blot assays revealed that algZ expression requires the sigma factor AlgT. The mapped algZ transcription start site revealed a consensus AlgT-dependent promoter that, when mutated, substantially reduced algZ transcription.
引用
收藏
页码:7297 / 7300
页数:4
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