The Urbilaterian Super-Hox cluster

被引：34

作者：

Butts, Thomas ^{[1
,2
]}

Holland, Peter W. H. ^{[1
,2
]}

Ferrier, David E. K. ^{[1
,2
]}

机构：

[1] Univ St Andrews, Gatty Marine Lab, St Andrews KY16 8LB, Fife, Scotland

[2] Univ Oxford, Dept Zool, Oxford OX1 3PS, England

来源：

TRENDS IN GENETICS | 2008年 / 24卷 / 06期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/j.tig.2007.09.006

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

引用

页码：259 / 262

页数：4

共 31 条

[1] The dawn of bilaterian animals:: the case of acoelomorph flatworms [J].

Baguñà, J ;

Riutort, M .

BIOESSAYS, 2004, 26 (10) :1046-1057

[2] Hox clusters and bilaterian phylogeny [J].

Balavoine, G ;

de Rosa, R ;

Adoutte, A .

MOLECULAR PHYLOGENETICS AND EVOLUTION, 2002, 24 (03) :366-373

[3] Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida [J].

Bourlat, Sarah J. ;

Juliusdottir, Thorhildur ;

Lowe, Christopher J. ;

Freeman, Robert ;

Aronowicz, Jochanan ;

Kirschner, Mark ;

Lander, Eric S. ;

Thorndyke, Michael ;

Nakano, Hiroaki ;

Kohn, Andrea B. ;

Heyland, Andreas ;

Moroz, Leonid L. ;

Copley, Richard R. ;

Telford, Maximilian J. .

NATURE, 2006, 444 (7115) :85-88

[4] The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster [J].

Brooke, NM ;

Garcia-Fernàndez, J ;

Holland, PWH .

NATURE, 1998, 392 (6679) :920-922

[5]

Brown SJ, 2002, GENETICS, V160, P1067

[6] Chromosomal mapping of ANTP class homeobox genes in amphioxus: piecing together ancestral genomes [J].

Castro, LFC ;

Hoiianda, PWH .

EVOLUTION & DEVELOPMENT, 2003, 5 (05) :459-465

[7] Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements [J].

Chourrout, D. ;

Delsuc, F. ;

Chourrout, P. ;

Edvardsen, R. B. ;

Rentzsch, F. ;

Renfer, E. ;

Jensen, M. F. ;

Zhu, B. ;

de Jong, P. ;

Steele, R. E. ;

Technau, U. .

NATURE, 2006, 442 (7103) :684-687

[8]

Coulier F, 2000, J EXP ZOOL, V288, P345, DOI 10.1002/1097-010X(20001215)288:4<345::AID-JEZ7>3.0.CO

[9]

2-Y

[10] A common plan for dorsoventral patterning in Bilateria [J].

DeRobertis, EM ;

Sasai, Y .

NATURE, 1996, 380 (6569) :37-40

← 1 2 3 4 →