Separation of components in lipid membranes induced by shape transformation

被引:12
作者
Gozdz, W. T. [1 ]
Bobrovska, N. [1 ]
Ciach, A. [1 ]
机构
[1] Polish Acad Sci, Inst Phys Chem, PL-01224 Warsaw, Poland
关键词
BAR DOMAINS; SPONTANEOUS CURVATURE; ORGANIZATION; TUBULATION; PROTEINS; VESICLES;
D O I
10.1063/1.4731646
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Vesicles composed of a two component membrane with each component characterized by different spontaneous curvature are investigated by minimization of the free energy consisting of Helfrich elastic energy and entropy of mixing. The results show that mixing and demixing of membrane components can be induced by elongating a vesicle or changing its volume, if one of the components forms a complex with macromolecules on the outer monolayer. The influence of elastic coefficients on the separation of components is also examined. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4731646]
引用
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页数:7
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