Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)

被引：3699

作者：

Bousquet, J. ^{[1
]}

Khaltaev, N. ^{[3
]}

Cruz, A. A. ^{[4
]}

Denburg, J. ^{[5
]}

Fokkens, W. J. ^{[6
]}

Togias, A. ^{[7
]}

Zuberbier, T. ^{[8
]}

Baena-Cagnani, C. E. ^{[9
,10
]}

Canonica, G. W. ^{[11
]}

van Weel, C. ^{[12
]}

Agache, I. ^{[13
]}

Ait-Khaled, N.

Bachert, C. ^{[14
]}

Blaiss, M. S. ^{[15
]}

Bonini, S. ^{[16
]}

Boulet, L. -P. ^{[17
,18
]}

Bousquet, P. -J. ^{[19
]}

Camargos, P. ^{[20
]}

Carlsen, K. -H. ^{[21
]}

Chen, Y. ^{[22
]}

Custovic, A. ^{[23
]}

Dahl, R. ^{[24
]}

Demoly, P. ^{[2
]}

Douagui, H. ^{[25
]}

Durham, S. R. ^{[26
]}

van Wijk, R. Gerth ^{[27
]}

Kalayci, O. ^{[28
]}

Kaliner, M. A. ^{[29
,30
]}

Kim, Y. -Y. ^{[31
]}

Kowalski, M. L.

Kuna, P. ^{[32
]}

Le, L. T. T. ^{[33
]}

Lemiere, C. ^{[34
]}

Li, J. ^{[35
]}

Lockey, R. F. ^{[36
]}

Mavale-Manuel, S. ^{[37
]}

Meltzer, E. O. ^{[38
]}

Mohammad, Y. ^{[39
]}

Mullol, J. ^{[40
]}

Naclerio, R. ^{[41
]}

Hehir, R. E. O. ^{[42
,43
]}

Ohta, K. ^{[44
]}

Ouedraogo, S. ^{[45
]}

Palkonen, S. ^{[46
]}

Papadopoulos, N. ^{[47
]}

Passalacqua, G. ^{[48
]}

Pawankar, R. ^{[49
]}

Popov, T. A. ^{[50
]}

Rabe, K. F. ^{[51
]}

Rosado-Pinto, J. ^{[52
]}

机构：

[1] Univ Hosp, Montpellier, France

[2] Hop Arnaud Villeneuve, INSERM, Univ Hosp Montpellier, U657, Montpellier, France

[3] GARD ARIA, Geneva, Switzerland

[4] Univ Fed Bahia, Sch Med, BR-41170290 Salvador, BA, Brazil

[5] McMaster Univ, AllerGen NCE, Hamilton, ON L8S 4L8, Canada

[6] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[7] NIAID, Bethesda, MD 20892 USA

[8] Charite, Allergy Ctr Charite, D-13353 Berlin, Germany

[9] WAO, Cordoba, Argentina

[10] Catholic Univ Cordoba, Cordoba, Argentina

[11] Univ Genoa, Allergy & Resp Dis Clin, Genoa, Italy

[12] Radboud Univ Nijmegen, Med Ctr, NL-6525 ED Nijmegen, Netherlands

[13] Transylvania Univ, Brasov, Romania

[14] Univ Hosp Ghent, UZG, Ghent, Belgium

[15] Univ Tennessee, Ctr Hlth Sci, Memphis, TN 38163 USA

[16] Univ Naples 2, INMM CNR, Rome, Italy

[17] Hop Laval, Inst Cardiol & Pneumol, Quebec City, PQ, Canada

[18] Univ Laval, Quebec City, PQ, Canada

[19] Univ Nimes Hosp, F-30006 Nimes, France

[20] Univ Fed Minas Gerais, Univ Hosp, Sch Med, Belo Horizonte, MG, Brazil

[21] Univ Oslo, Rikshosp, Norwegian Sch Sport Sci, Fac Med, N-0027 Oslo, Norway

[22] Capital Inst Pediat, Asthma Clin & Educ Ctr, Natl Cooperat Grp Pediat Res Asthma, Beijing, Peoples R China

[23] Univ Manchester, Manchester, Lancs, England

[24] Aarhus Univ Hosp, DK-8000 Aarhus, Denmark

[25] Ctr Hosp Univ Beni Messous, Algiers, Algeria

[26] Univ London Imperial Coll Sci Technol & Med, London, England

[27] Erasmus MC, Rotterdam, Netherlands

[28] Pediat Allergy & Asthma Unit, Ankara, Turkey

[29] Geo Washington Univ, Sch Med, Washington, DC USA

[30] Inst Asthma & Allergy, Chevy Chase, MD USA

[31] Seoul Natl Univ Hosp, Seoul 110744, South Korea

[32] Med Univ Lodz, Barlicki Univ Hosp, Lodz, Poland

[33] Univ Med & Pharm, Ho Chi Minh City, Vietnam

[34] Univ Montreal, Montreal, PQ, Canada

[35] First Affiliated Hosp, Guangzhou Med Sch, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China

[36] Univ S Florida, Coll Med, Tampa, FL 33620 USA

[37] Childrens Hosp, Maputo, Mozambique

[38] Univ Calif San Diego, Allergy & Asthma Med Grp & Res Ctr, San Diego, CA 92103 USA

[39] Tishreen Univ Sch Med, Latakia, Syria

[40] Hosp Clin IDIBAPS, Barcelona, Catalonia, Spain

[41] Univ Chicago, Chicago, IL 60637 USA

[42] Alfred Hosp, Melbourne, Vic, Australia

[43] Monash Univ, Melbourne, Vic 3004, Australia

[44] Teikyo Univ, Sch Med, Tokyo 173, Japan

[45] Ctr Hosp Univ Pediat Charles de Gaulle, Ouagadougou, Burkina Faso

[46] EFA European Federat Allergy & Airways Dis Patien, Brussels, Belgium

[47] Univ Athens, Allergy Res Ctr, Athens, Greece

[48] Univ Genoa, Genoa, Italy

[49] Nippon Med Sch, Bunkyo Ku, Tokyo 113, Japan

[50] Med Univ Sofia, Clin Allergy & Asthma, Sofia, Bulgaria

来源：

ALLERGY | 2008年 / 63卷

基金：

英国医学研究理事会;

关键词：

ARIA; asthma; guideline; management; rhinitis;

D O I：

10.1111/j.1398-9995.2007.01620.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups and of all ages suffer from allergic rhinitis. It affects social life, sleep, school and work and its economic impact is substantial. Risk factors for allergic rhinitis are well identified. Indoor and outdoor allergens as well as occupational agents cause rhinitis and other allergic diseases. The role of indoor and outdoor pollution is probably very important, but has yet to be fully understood both for the occurrence of the disease and its manifestations. In 1999, during the Allergic Rhinitis and its Impact on Asthma (ARIA) WHO workshop, the expert panel proposed a new classification for allergic rhinitis which was subdivided into 'intermittent' or 'persistent' disease. This classification is now validated. The diagnosis of allergic rhinitis is often quite easy, but in some cases it may cause problems and many patients are still under-diagnosed, often because they do not perceive the symptoms of rhinitis as a disease impairing their social life, school and work. The management of allergic rhinitis is well established and the ARIA expert panel based its recommendations on evidence using an extensive review of the literature available up to December 1999. The statements of evidence for the development of these guidelines followed WHO rules and were based on those of Shekelle et al. A large number of papers have been published since 2000 and are extensively reviewed in the 2008 Update using the same evidence-based system. Recommendations for the management of allergic rhinitis are similar in both the ARIA workshop report and the 2008 Update. In the future, the GRADE approach will be used, but is not yet available. Another important aspect of the ARIA guidelines was to consider co-morbidities. Both allergic rhinitis and asthma are systemic inflammatory conditions and often co-exist in the same patients. In the 2008 Update, these links have been confirmed. The ARIA document is not intended to be a standard-of-care document for individual countries. It is provided as a basis for physicians, health care professionals and organizations involved in the treatment of allergic rhinitis and asthma in various countries to facilitate the development of relevant local standard-of-care documents for patients.

引用

页码：8 / +

页数：154

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