Significance of microbleeds in patients with transient ischaemic attack

被引：39

作者：

Fluri, F. ^{[1
]}

Jax, F. ^{[2
]}

Amort, M. ^{[1
]}

Wetzel, S. G. ^{[2
]}

Lyrer, P. A. ^{[1
]}

Katan, M. ^{[1
]}

Hatz, F. ^{[1
]}

Engelter, S. T. ^{[1
]}

机构：

[1] Univ Basel Hosp, Dept Clin Neurol, CH-4031 Basel, Switzerland

[2] Univ Basel Hosp, Dept Neuroradiol, CH-4031 Basel, Switzerland

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 2012年 / 19卷 / 03期

关键词：

diffusion-weighted imaging; microbleeds; outcome; recurrent stroke; transient ischaemic attack; STROKE; RISK; CLASSIFICATION;

D O I：

10.1111/j.1468-1331.2011.03522.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and purpose: The aim of this study was to determine the prognostic significance of microbleeds in TIA-patients. In patients with a transient ischaemic attack (TIA), the prognostic value of microbleeds is unknown. Methods: In 176 consecutive TIA patients, the number, size, and location of microbleeds with or without acute ischaemic lesions were assessed. We compared microbleed- positive and microbleed- negative patients with regard to the end-point stroke within 3 months. Results: Four of the seven patients with subsequent stroke had microbleeds. Microbleed-positive patients had a higher risk for stroke [ odds ratios (OR) 8.91, 95% CI 1.87-42.51, P < 0.01] than those without microbleeds. Microbleed-positive patients with accompanying acute ischaemic lesions had a higher stroke risk than those with neither an acute ischaemia nor a microbleed (OR 6.20, 95% CI 1.10-35.12; P = 0.04). Conclusion: Microbleeds alone or in combination with acute ischaemic lesions may increase the risk for subsequent ischaemic stroke after TIA within 3 months.

引用

页码：522 / 524

页数：3

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