The analysis of synaptically generated traveling waves

被引:76
作者
Ermentrout, B [1 ]
机构
[1] Univ Pittsburgh, Dept Math, Pittsburgh, PA 15260 USA
基金
美国国家科学基金会;
关键词
waves; propagation; integrate-and-fire; biophysical models;
D O I
10.1023/A:1008822117809
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Mathematical and computational models for the propagation of activity in excitatorily coupled neurons are simulated and analyzed. The basic measurable quantity-velocity-is found for a wide class of models. Numerical bifurcation techniques, asymptotic analysis, and numerical simulations are used to show that there are distinct scaling laws for the velocity as a function of a variety of parameters. In particular, the obvious linear relationships between speed and spatial spread or synaptic decay rate are shown. More surprisingly, it is shown that the velocity scales as a power law with synaptic coupling strength and that the exponent is dependent only on the rising phase of the synapse.
引用
收藏
页码:191 / 208
页数:18
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