The therapeutic antibodies market to 2008

被引:80
作者
Pavlou, AK [1 ]
Belsey, MJ [1 ]
机构
[1] Biotechnol Anal Team, London NW3 5JJ, England
关键词
monoclonal antibody; chimeric; murine; humanized; fabs; fully human; market analysis;
D O I
10.1016/j.ejpb.2004.11.007
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The therapeutic biologics market is currently dominated by recombinant protein products. However, many of these products are mature, and growth of the biologics market will increasingly rely on the expansion of the therapeutic monoclonal antibody sector. Successive technology waves have driven the growth of the monoclonal antibody sector, which is currently dominated by chimeric antibodies. Chimeric products, led by Remicade and Rituxan, will continue to drive market share through to 2008. However, over the forecast period, humanized and fully human monoclonal antibodies, together with technologies such as Fabs and conjugated antibodies, will play an increasingly important role, driving monoclonal antibody market growth at a forecast compound annual growth rate of 20.9%, to reach $16.7 billion by 2008. In terms of therapeutic focus, the monoclonal antibody market is heavily focused on oncology and arthritis, immune and inflammatory disorders, and products within these therapeutic areas are set to continue to be the key growth drivers over the forecast period. Underlying the growth of the market is the evolution of the monoclonal antibody company business model, set to transition towards the highly successful innovator model. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:389 / 396
页数:8
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