Biocompatibility of modified silica-protein composite layers

被引：42

作者：

Brasack, I

Böttcher, H

Hempel, U

机构：

[1] Feinchem GmbH Sebnitz, D-01855 Sebnitz, Germany

[2] TU Dresden, Inst Physiol Chem, D-01109 Dresden, Germany

来源：

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2000年 / 19卷 / 1-3期

关键词：

biocomposite layers; silica; gelatine; biocompatibility;

D O I：

10.1023/A:1008763900729

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Biocomposite layers of silica and various bone-relevant proteins such as collagen, gelatine and commercial collagen hydrolysate can be obtained from coatings of silica sols mixed with proteins in water/dioxane. Investigations into the mechanical and cell proliferation properties for different sol parameters (pH, solvent), type and concentration of proteins, annealing and crosslinking of the biocomposite layers revealed that such coatings are highly biocompatible with excellent mechanical properties.

引用

页码：479 / 482

页数：4

共 16 条

[1]

Addadi L., 1992, ANGEW CHEM, V104, P159

[2]

[Anonymous], 1992, 10993 ISO 5

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