Synthesis of 1′-C-fluoromethyladenosine

被引：6

作者：

Damont, Annelaure ^{[1
]}

Dukhan, David ^{[1
]}

Gosselin, Gilles ^{[1
]}

Peyronnet, Jerome ^{[1
]}

Storer, Richard ^{[2
]}

机构：

[1] Univ Montpellier 2, CNRS, Lab Cooperatif Idenix, F-34095 Montpellier 5, France

[2] Cap Gamma, Lab Chim Med, Montpellier, France

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2007年 / 26卷 / 10-12期

关键词：

1 '-C-fluoromethyl branched ribonucleosides; exo-glycal; fluorination;

D O I：

10.1080/15257770701542165

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In search for new antiviral agents, we have been interested in 1'-C-fluoromethyl branched ribonucleosides. In this paper we describe the synthesis of 1'-C-fluoromethyladenosine via electrophilic fluorination of exo-glycal.

引用

页码：1431 / 1434

页数：4

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