Versatile synthesis of L-alpha-amino acids stereospecifically labelled on the beta-carbon atom

被引：7

作者：

Beresford, KJM ^{[1
]}

Young, DW ^{[1
]}

机构：

[1] UNIV SUSSEX,SCH CHEM & MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND

来源：

TETRAHEDRON | 1996年 / 52卷 / 29期

关键词：

D O I：

10.1016/0040-4020(96)00521-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Inversion of the stereochemistry at the alpha-centre of stereospecifically labelled samples of (2S)-isoserine (7) using a sequence involving an intramolecular substitution reaction has allowed synthesis of the stereospecifically labelled aziridines (19) to be completed. These are synthons for a very versatile preparation of L-amino acids which are stereospecifically labelled at the beta-carbon atom. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：9891 / 9900

页数：10

共 9 条

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