Gold(III) chloride-catalyzed addition reactions of electron-rich arenes to methyl vinyl ketone

被引：150

作者：

Dyker, G

Muth, E

Hashmi, ASK

Ding, L

机构：

[1] Ruhr Univ Bochum, Dept Chem, D-44780 Bochum, Germany

[2] Univ Stuttgart, Inst Organ Chem, D-70569 Stuttgart, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2003年 / 345卷 / 11期

关键词：

acids; aromatic substitution; gold; homogeneous catalysis; Lewis acids; Michael acceptors;

D O I：

10.1002/adsc.200303098

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

For the reaction of alpha,beta-unsaturated ketones with electron-rich arenes catalyzed by gold(III) chloride both, a Friedel-Crafts-type mechanism and an initial metallation, are evaluated. Gold(III) chloride has proven to be an efficient catalyst under very moderate reaction conditions, however, in the case of sterically demanding products HBF4 turned out to be the superior catalyst.

引用

页码：1247 / 1252

页数：6

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