Management of complications of cirrhosis in patients awaiting liver transplantation

被引:49
作者
Cardenas, A [1 ]
Ginès, P [1 ]
机构
[1] Univ Barcelona, Liver Unit, Inst Malalties Disgest, Hosp Clin,IDIBAPS, E-08036 Barcelona, Spain
基金
美国国家航空航天局;
关键词
D O I
10.1016/j.jhep.2004.12.007
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
As the demand for OLT increases, patients with advanced cirrhosis will end up spending a longer time waiting in the list with an increased risk of developing further decompensation and dying. Only the expansion of the donor pool will have a major impact on the survival of patients; however, this seems to be extremely challenging given that use of marginal donors and living related liver transplantation has not made a significant impact on waiting times. Therefore, both prevention and effective treatment of complications such as ascites, dilutional hyponatremia, hepatorenal syndrome, spontaneous bacterial peritonitis, hepatic encephalopathy and variceal bleeding may improve the likelihood of a patient surviving until OLT. © 2004 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:S124 / S133
页数:10
相关论文
共 88 条
[1]  
Abbasoglu O, 1998, CLIN TRANSPLANT, V12, P263
[2]   Somatostatin and analogues in portal hypertension [J].
Abraldes, JG ;
Bosch, J .
HEPATOLOGY, 2002, 35 (06) :1305-1312
[3]   Evolution of liver transplantation in Europe: Report of the European liver transplant registry [J].
Adam, P ;
McMaster, P ;
O'Grady, JG ;
Castaing, D ;
Klempnauer, JL ;
Jamieson, N ;
Neuhaus, P ;
Lerut, J ;
Salizzoni, M ;
Pollard, S ;
Muhlbacher, F ;
Rogiers, X ;
Valdecasas, JCG ;
Berenguer, J ;
Jaeck, D ;
Gonzalez, EM .
LIVER TRANSPLANTATION, 2003, 9 (12) :1231-1243
[4]   Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trial [J].
Akriviadis, E ;
Botla, R ;
Briggs, W ;
Han, S ;
Reynolds, T ;
Shakil, O .
GASTROENTEROLOGY, 2000, 119 (06) :1637-1648
[5]   Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide [J].
Angeli, P ;
Volpin, R ;
Gerunda, G ;
Craighero, R ;
Rone, P ;
Merenda, R ;
Amodio, P ;
Sticca, A ;
Caregaro, L ;
Maffei-Faccioli, A ;
Gatta, A .
HEPATOLOGY, 1999, 29 (06) :1690-1697
[6]  
[Anonymous], 1984, HEPATOLOGY, V4, p107S, DOI 10.1002/hep.1840040725
[7]  
Arroyo V, 1996, HEPATOLOGY, V23, P164, DOI 10.1002/hep.510230122
[8]   PROGNOSTIC VALUE OF SPONTANEOUS HYPONATREMIA IN CIRRHOSIS WITH ASCITES [J].
ARROYO, V ;
RODES, J ;
GUTIERREZLIZARRAGA, MA ;
REVERT, L .
AMERICAN JOURNAL OF DIGESTIVE DISEASES, 1976, 21 (03) :249-256
[9]   Ascites and hepatorenal syndrome in cirrhosis: pathophysiological basis of therapy and current management [J].
Arroyo, V ;
Colmenero, J .
JOURNAL OF HEPATOLOGY, 2003, 38 :S69-S89
[10]   Early administration of somatostatin and efficacy of sclerotherapy in acute oesophageal variceal bleeds: the European acute bleeding oesophageal variceal episodes (ABOVE) randomised trial [J].
Avgerinos, A ;
Nevens, F ;
Raptis, S ;
Fevery, J ;
Armonis, A ;
Manolakopoulos, S ;
Poulianos, G ;
Tzathas, C ;
Katsaros, D ;
Soutos, D ;
Zacharopoulose, A ;
Adler, M ;
Bourgeois, N ;
Bac, DJ ;
VanBuuren, HR ;
Decruyenaere, J ;
Elewaut, A ;
Deman, M ;
Lepoutre, L ;
VanderSpek, P ;
Hautekeete, M ;
Reynaert, H ;
Buyse, M ;
Ritter, L ;
Burtin, B ;
Darcis, T ;
Ioannou, J ;
Natens, J ;
Natens, O .
LANCET, 1997, 350 (9090) :1495-1499