Synthesis of sulfated beta-1,6-linked oligosaccharide mimetics: A novel potent inhibitor of HIV replication

被引:54
作者
Suhara, Y
Ichikawa, M
Hildreth, JEK
Ichikawa, Y
机构
[1] Dept. of Pharmacol. and Molec. Sci., Johns Hopkins Univ. Sch. of Medicine, Baltimore
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0040-4039(96)00327-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel sulfated beta(1-->6)-linked oligosaccharide mimetics has been synthesized and found to be a potent inhibitor of HIV replication, with an IC50 of 1 mu M. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:2549 / 2552
页数:4
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