APECED: a monogenic autoimmune disease providing new clues to self-tolerance

被引:74
作者
Peterson, P [1 ]
Nagamine, K
Scott, H
Heino, M
Kudoh, J
Shimizu, N
Antonarakis, SE
Krohn, KJE
机构
[1] Univ Tampere, Inst Med Technol, SF-33101 Tampere, Finland
[2] Univ Tampere, Univ Hosp, SF-33101 Tampere, Finland
[3] Keio Univ, Sch Med, Dept Mol Biol, Shinjuku Ku, Tokyo 160, Japan
[4] Univ Geneva, Sch Med, Dept Genet & Microbiol, Lab Human Mol Genet, Geneva 4, Switzerland
来源
IMMUNOLOGY TODAY | 1998年 / 19卷 / 09期
基金
日本学术振兴会;
关键词
D O I
10.1016/S0167-5699(98)01293-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The cloning of AIRE, the gene for autoimmune polyendocrinopathy-candidiais-ectodermal dystrophy (APECED) promises to unravel some of the mysteries of autoimmunity. Here, Part Peterson and colleagues discuss recent studies of AIRE and the implications for disease therapy.
引用
收藏
页码:384 / 386
页数:3
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