Serum procalcitonin for discrimination of blood contamination from bloodstream infection due to coagulase-negative staphylococci

被引：133

作者：

Schuetz, P.

Mueller, B.

Trampuz, A.

机构：

[1] Univ Basel Hosp, Dept Infect Dis, CH-4031 Basel, Switzerland

[2] Univ Basel Hosp, Hosp Epidemiol, CH-4031 Basel, Switzerland

[3] Univ Basel Hosp, Dept Internal Med, CH-4031 Basel, Switzerland

来源：

INFECTION | 2007年 / 35卷 / 05期

关键词：

D O I：

10.1007/s15010-007-7065-0

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The diagnostic value of serum procalcitonin (PCT) to distinguish blood contamination from bloodstream infection (BSI) due to coagulase-negative staphylococci was evaluated. Patients with BSI had higher PCT concentration than those with blood contamination at day -1, day 0 and day +1 with regard to blood culture collection (p < 0.05), whereas serum C-reactive protein values were significantly higher only on day +1. At a cutoff of 0.1 ng/dl, PCT had a sensitivity of 86% and 100%, and a specificity of 60% and 80% for the diagnosis of BSI on day -1 and 0, respectively. In addition to clinical and microbiological parameters, PCT may help discriminating blood contamination from BSI due coagulase-negative staphylococci.

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收藏

页码：352 / 355

页数：4

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