RGS protein and G protein interactions: A little help from their friends

被引:37
作者
Hepler, JR [1 ]
机构
[1] Emory Univ, Sch Med, Dept Pharmacol, Rollins Res Ctr 5001, Atlanta, GA 30322 USA
关键词
SIGNALING RGS; DRUG TARGETS; REGULATORS; COMPARTMENTATION; TRANSDUCTION; LOCALIZATION; SPECIFICITY; ACTIVATION; BINDING;
D O I
10.1124/mol.64.3.547
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:547 / 549
页数:3
相关论文
共 22 条
[1]   Dimerization: An emerging concept for G protein-coupled receptor ontogeny and function [J].
Angers, S ;
Salahpour, A ;
Bouvier, M .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2002, 42 :409-435
[2]   G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction [J].
Brady, AE ;
Limbird, LE .
CELLULAR SIGNALLING, 2002, 14 (04) :297-309
[3]   The regulator of G protein signaling family [J].
De Vries, L ;
Zheng, B ;
Fischer, T ;
Elenko, E ;
Farquhar, MG .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2000, 40 :235-271
[4]   Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase Cβ1 [J].
Dowal, L ;
Elliott, J ;
Popov, S ;
Wilkie, TM ;
Scarlata, S .
BIOCHEMISTRY, 2001, 40 (02) :414-421
[5]  
Gold SJ, 1997, J NEUROSCI, V17, P8024
[6]   Regulation of G protein-coupled receptor signaling by scaffold proteins [J].
Hall, RA ;
Lefkowitz, RJ .
CIRCULATION RESEARCH, 2002, 91 (08) :672-680
[7]   Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling [J].
Hollinger, S ;
Hepler, JR .
PHARMACOLOGICAL REVIEWS, 2002, 54 (03) :527-559
[8]   Protein-protein interactions at G-protein-coupled receptors [J].
Milligan, G ;
White, JH .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2001, 22 (10) :513-518
[9]   Regulators of G-protein signalling as new central nervous system drug targets [J].
Neubig, RR ;
Siderovski, DR .
NATURE REVIEWS DRUG DISCOVERY, 2002, 1 (03) :187-197
[10]   New determinants of receptor-effector coupling: Trafficking and compartmentation in membrane microdomains [J].
Ostrom, RS .
MOLECULAR PHARMACOLOGY, 2002, 61 (03) :473-476