On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis

被引:22
作者
Cook, D [1 ]
Heyland, D
Marshall, J
机构
[1] McMaster Univ, Dept Med, Hamilton, ON, Canada
[2] McMaster Univ, Dept Clin Epidemiol, Hamilton, ON L8S 4L8, Canada
[3] Queens Univ, Dept Med, Kingston, ON K7L 3N6, Canada
[4] Univ Toronto, Dept Surg, Toronto, ON, Canada
关键词
D O I
10.1007/s001340000828
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
[No abstract available]
引用
收藏
页码:347 / 354
页数:8
相关论文
共 41 条
[1]  
[Anonymous], 1996, Clin Intensive Care
[2]   Implementation of bronchoscopic techniques in the diagnosis of ventilator-associated pneumonia to reduce antibiotic use [J].
Bonten, MJM ;
Bergmans, DCJJ ;
Stobberingh, EE ;
vanderGeest, S ;
DeLeeuw, PW ;
vanTiel, FH ;
Gaillard, CA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 156 (06) :1820-1824
[3]   DISCORDANCE BETWEEN METAANALYSES AND LARGE-SCALE RANDOMIZED, CONTROLLED TRIALS - EXAMPLES FROM THE MANAGEMENT OF ACUTE MYOCARDIAL-INFARCTION [J].
BORZAK, S ;
RIDKER, PM .
ANNALS OF INTERNAL MEDICINE, 1995, 123 (11) :873-877
[4]   A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation [J].
Cook, D ;
Guyatt, G ;
Marshall, J ;
Leasa, D ;
Fuller, H ;
Hall, R ;
Peters, S ;
Rutledge, F ;
Griffith, L ;
McLellan, A ;
Wood, G ;
Kirby, A .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (12) :791-797
[5]   Adjudicating ventilator-associated pneumonia in a randomized trial of critically ill patients [J].
Cook, D ;
Walter, S ;
Freitag, A ;
Guyatt, G ;
Devitt, H ;
Meade, M ;
Griffith, L ;
Sarabia, A ;
Fuller, H ;
Turner, W ;
Gough, K .
JOURNAL OF CRITICAL CARE, 1998, 13 (04) :159-163
[6]  
Cook D, 1997, INTENSIVE CARE WORLD, V14, P68
[7]   RISK-FACTORS FOR GASTROINTESTINAL-BLEEDING IN CRITICALLY ILL PATIENTS [J].
COOK, DJ ;
FULLER, HD ;
GUYATT, GH ;
MARSHALL, JC ;
LEASA, D ;
HALL, R ;
WINTON, TL ;
RUTLEDGE, F ;
TODD, TJR ;
ROY, P ;
LACROIX, J ;
GRIFFITH, L ;
WILLAN, A ;
NOSEWORTHY, T ;
POWLES, P ;
OPPENHEIMER, L ;
HEWSON, J ;
LANG, J ;
LEE, H ;
GUSLITS, B ;
HEULE, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (06) :377-381
[8]   Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients [J].
Cook, DJ ;
Walter, SD ;
Cook, RJ ;
Griffith, LE ;
Guyatt, GH ;
Leasa, D ;
Jaeschke, RZ ;
Brun-Buisson, C .
ANNALS OF INTERNAL MEDICINE, 1998, 129 (06) :433-440
[9]   NOSOCOMIAL PNEUMONIA AND THE ROLE OF GASTRIC PH - A METAANALYSIS [J].
COOK, DJ ;
LAINE, LA ;
GUYATT, GH ;
RAFFIN, TA .
CHEST, 1991, 100 (01) :7-13
[10]   STRESS-ULCER PROPHYLAXIS IN THE CRITICALLY ILL - A METAANALYSIS [J].
COOK, DJ ;
WITT, LG ;
COOK, RJ ;
GUYATT, GH .
AMERICAN JOURNAL OF MEDICINE, 1991, 91 (05) :519-527