LOCATE: a mammalian protein subcellular localization database

被引：105

作者：

Sprenger, Josefine ^{[1
]}

Fink, J. Lynn ^{[1
]}

Karunaratne, Seetha ^{[1
]}

Hanson, Kelly ^{[1
]}

Hamilton, Nicholas A. ^{[1
]}

Teasdale, Rohan D. ^{[1
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, ARC Ctr Excellence Bioinformat, St Lucia, Qld 4072, Australia

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

基金：

英国医学研究理事会; 澳大利亚研究理事会;

关键词：

D O I：

10.1093/nar/gkm950

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

LOCATE is a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of mouse and human proteins. Over the past 2 years, the data in LOCATE have grown substantially. The database now contains high-quality localization data for 20 of the mouse proteome and general localization annotation for nearly 36 of the mouse proteome. The proteome annotated in LOCATE is from the RIKEN FANTOM Consortium Isoform Protein Sequence sets which contains 58 128 mouse and 64 637 human protein isoforms. Other additions include computational subcellular localization predictions, automated computational classification of experimental localization image data, prediction of protein sorting signals and third party submission of literature data. Collectively, this database provides localization proteome for individual subcellular compartments that will underpin future systematic investigations of these regions. It is available at http://locate.imb.uq.edu.au/.

引用

页码：D230 / D233

页数：4

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