Parvovirus B19 infection in pregnancy: new insights and management

被引：63

作者：

de Jong, E. P. ^{[2
]}

Walther, F. J. ^{[3
]}

Kroes, A. C. M. ^{[4
]}

Oepkes, D. ^{[1
]}

机构：

[1] Leiden Univ, Dept Obstet, Med Ctr, NL-2300 RC Leiden, Netherlands

[2] Julianas Childrens Hosp, Dept Pediat, HAGA Hosp, The Hague, Netherlands

[3] Leiden Univ, Dept Pediat, Med Ctr, Div Neonatol, NL-2300 RC Leiden, Netherlands

[4] Leiden Univ, Dept Med Microbiol, Med Ctr, NL-2300 RC Leiden, Netherlands

来源：

PRENATAL DIAGNOSIS | 2011年 / 31卷 / 05期

关键词：

parvovirus B19; fetal infection; hydrops fetalis; intrauterine blood transfusion; management; MATERNAL INFECTION; FETAL ANEMIA; CELLULAR CORECEPTOR; HYDROPS; DIAGNOSIS; RISK; THROMBOCYTOPENIA; CYTOMEGALOVIRUS; TRANSMISSION; PATHOGENESIS;

D O I：

10.1002/pd.2714

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In this article, we review the virology, pathology, epidemiology and clinical spectrum of intrauterine human parvovirus B19 (B19V) infection, including intrauterine fetal death, non-immune hydrops fetalis, thrombocytopenia and neurological manifestations such as pediatric stroke and perivascular calcifications. In addition, we discuss the new insights into the neurodevelopmental outcome of intrauterine B19V infection. Current diagnosis and management of B19V infection is summarized, including a diagnostic and follow-up flowchart for practical clinical use. Copyright (C) 2011 John Wiley & Sons, Ltd.

引用

页码：419 / 425

页数：7

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