Systemic lupus erythematosus associated with acute Epstein-Barr virus infection

被引：40

作者：

Dror, Y

Blachar, Y

Cohen, P

Livni, N

Rosenmann, E

Ashkenazi, A

机构：

[1] Kaplan Hosp, Dept Pediat B, IL-76100 Rehovot, Israel

[2] Kaplan Hosp, Pediat Emergency Dept, IL-76100 Rehovot, Israel

[3] Kaplan Hosp, Dept Pathol, IL-76100 Rehovot, Israel

[4] Hadassah Univ Hosp, Dept Pathol, IL-91120 Jerusalem, Israel

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1998年 / 32卷 / 05期

关键词：

systemic lupus erythematosus; Epstein-Barr virus;

D O I：

10.1016/S0272-6386(98)70140-4

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Systemic lupus erythematosus (SLE) is a multisystem disease of unknown origin, characterized by a variety of autoimmune phenomena. Viruses have long been postulated to play a role in its pathogenesis, Several observations suggested a link between Epstein-Barr virus (EBV) and SLE, We describe a 14-year-old girl who presented with acute onset of SLE concurrently with clinical and laboratory findings consistent with EBV-induced infectious mononucleosis (IM). Evidence for acute EBV infection was confirmed by serological studies and detection of specific EBV antigens on kidney biopsy. This close association between EBV and SLE suggests a possible role of the virus in the pathogenesis of SLE in this patient. (C) 1998 by the National Kidney Foundation, Inc.

引用

页码：825 / 828

页数：4

共 16 条

[1] COMPLICATIONS OF INFECTION WITH EPSTEIN-BARR VIRUS DURING CHILDHOOD - A STUDY OF CHILDREN ADMITTED TO THE HOSPITAL [J].