Slow right prefrontal transcranial magnetic stimulation as a treatment for medication-resistant depression: A double-blind, placebo-controlled study

被引：71

作者：

Kauffmann, CD ^{[1
]}

Cheema, MA ^{[1
]}

Miller, BE ^{[1
]}

机构：

[1] E Tennessee State Univ, Dept Psychiat, Johnson City, TN 37614 USA

来源：

DEPRESSION AND ANXIETY | 2004年 / 19卷 / 01期

关键词：

TMS; rTMS; transcranial magnetic stimulation; depression;

D O I：

10.1002/da.10144

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Over the past decade, efforts have been made. to assess the positive therapeutic effects of transcranial magnetic stimulation (TMS) by altering the excitability of the brain. We conducted a double-blind, placebo-controlled study to assess the efficacy of tight prefrontal slow repetitive TMS in patients with treatment refractory major depression. This pilot study supports the therapeutic potential of rTMS in the low-frequency range of 1 Hz on right prefrontal cortex for the treatment of refractory major depression. Additional studies will be necessary to assess the efficacy of rTMS with different indices (frequency, intensity, and stimulation site) for major depression and other psychiatric diseases. (C) 2004 Wiley-Liss, Inc.

引用

页码：59 / 62

页数：4

共 22 条

[1]

BARKER AT, 1985, LANCET, V1, P1106

[2]

BARKER AT, 1985, ELECTROENCEPHALOGR C, V61, P570

[3] Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation [J].

Chen, R ;

Classen, J ;

Gerloff, C ;

Celnik, P ;

Wassermann, EM ;

Hallett, M ;

Cohen, LG .

NEUROLOGY, 1997, 48 (05) :1398-1403

[4] MAGNETIC STIMULATION - DETERMINATION OF COIL CURRENT FLOW DIRECTION [J].

CHIAPPA, KH ;

CROS, D ;

COHEN, D .

NEUROLOGY, 1991, 41 (07) :1154-1155

[5]

Feinsod M, 1998, Depress Anxiety, V7, P65

[6] Mood improvement following daily left prefrontal repetitive transcranial magnetic stimulation in patients with depression: A placebo-controlled crossover trial [J].

George, MS ;

Wassermann, EM ;

Kimbrell, TA ;

Little, JT ;

Williams, WE ;

Danielson, AL ;

Greenberg, BD ;

Hallett, M ;

Post, RM .

AMERICAN JOURNAL OF PSYCHIATRY, 1997, 154 (12) :1752-1756

[7] Transcranial magnetic stimulation -: Applications in neuropsychiatry [J].

George, MS ;

Lisanby, SH ;

Sackeim, HA .

ARCHIVES OF GENERAL PSYCHIATRY, 1999, 56 (04) :300-311

[8]

George MS, 1996, J NEUROPSYCH CLIN N, V8, P172

[9]

George MS., 1994, Depression, V2, P59

[10]

GRISARU N, 1994, EUR NEUROPSYCHOPHARM, V4, P287

← 1 2 3 →