ESHRE PGD Consortium data collection V: Cycles from January to December 2002 with pregnancy follow-up to October 2003

被引：80

作者：

Harper, JC

Boelaert, K

Geraedts, J

Harton, G

Kearns, WG

Moutou, C

Muntjewerff, N

Repping, S

SenGupta, S

Scriven, PN

Traeger-Synodinos, J

Vesela, K

Wilton, L

Sermon, KD

机构：

[1] UCL, UCL Ctr PGD, Dept Obstet & Gynecol, London WC1E 6HX, England

[2] Univ Hosp, Ctr Med Genet, B-1090 Brussels, Belgium

[3] Free Univ Brussels, Sch Med, B-1090 Brussels, Belgium

[4] Univ Hosp Maastricht, Dept Clin Genet, PGD Working Grp Maastricht, NL-6202 AZ Maastricht, Netherlands

[5] Genet & IVF Inst, Fairfax, VA 22031 USA

[6] Shady Grove Ctr Preimplantat Genet, Rockville, MD 20850 USA

[7] SIHCUS CMCO, Serv Biol Reprod, F-67303 Schiltigheim, France

[8] Acad Med Ctr, Ctr Reprod Med, Fertil Lab, NL-1105 AZ Amsterdam, Netherlands

[9] Guys Hosp, Guys & St Thomas NHS Fdn Trust, Dept Cytogenet, London SE1 9RT, England

[10] Guys Hosp, Guys & St Thomas NHS Fdn Trust, Ctr Preimplantat Genet Diag, London SE1 9RT, England

[11] Univ Athens, St Sophias Childrens Hosp, Med Genet Lab, Athens 11527, Greece

[12] Sanatorium Repromeda, Brno 61500, Czech Republic

[13] Melbourne IVF, Melbourne, Vic 3002, Australia

来源：

HUMAN REPRODUCTION | 2006年 / 21卷 / 01期

关键词：

aneuploidy screening; preimplantation genetic diagnosis; embryo biopsy; PGS; PGD;

D O I：

10.1093/humrep/dei292

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The fifth report of the ESHRE PGD Consortium is presented (data collection V). For the first time, the cycle data were collected for one calendar year (2002) in the following October, so that data collection was complete for pregnancies and babies. The data were collected using a Filemaker Pro database and divided into referrals, cycles, pregnancies and babies. There are currently 66 active centres registered with the consortium; however, the data presented here were obtained from 43 centres and included 1603 referrals, 2219 cycles, 485 pregnancies and 382 babies born. The cycle data were divided into preimplantation genetic diagnosis (PGD) for inherited disorders (including chromosome abnormalities, sexing for X-linked disease and monogenic disorders), aneuploidy screening (PGS) and the use of PGD for social sexing. Data collection V is compared with the previous cumulative data collection (I-IV), which comprised 4058 PGD/PGS cycles that reached oocyte retrieval.

引用

页码：3 / 21

页数：19

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