Optimal production of curdlan by Agrobacterium sp with feedback inferential control of optimal pH profile

被引：44

作者：

Lee, JH ^{[1
]}

Park, YH

机构：

[1] Chosun Univ, Dept Chem Engn, Kwangju 501759, South Korea

[2] Korea Res Inst Biosci & Biotechnol, Biotechnol Res Div, Taejon, South Korea

来源：

BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 07期

关键词：

curdlan; dissolved oxygen; inferential control; optimal control;

D O I：

10.1023/A:1010374519891

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The pH control was important for curdlan production with Agrobacterium sp. ATCC31750. Specific cell growth rate was the highest at pH 7 and the specific curdlan production rate was at pH 5.5. The pH profiles maximizing curdlan production was changed from pH 7 optimal for cell growth to pH 5.5 optimal for curdlan production after ammonium consumption. The feedback inferential control methods, with easily measurable variables such as NaOH addition for pH control and dissolved oxygen (DO), were also applied. The pH was successfully controlled to follow optimal profiles and the maximal production of curdlan (60 g l(-1) in 120 h) was achieved with feedback optimal control.

引用

页码：525 / 530

页数：6

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