The uniqueness of being a neurotrophin receptor

被引：158

作者：

Lee, FS

Kim, AH

Khursigara, G

Chao, MV ^{[1
]}

机构：

[1] NYU, Sch Med, Mol Neurobiol Program, Skirball Inst Biomol Med,Dept Cell Biol & Physiol, New York, NY 10016 USA

[2] Cornell Univ, Weill Med Coll, New York, NY 10021 USA

[3] NYU, Sch Med, Dept Neurosci, New York, NY 10016 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0959-4388(00)00209-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Neurotrophins rely on Trk tyrosine kinase and p75 receptors for signal transduction. Recently, other roles for these receptors have been identified. Many questions have been raised about the mechanism by which these receptors mediate diverse cellular functions. Studies indicate a great deal of neurotrophin signaling specificity may stem from ligand-receptor selectivity and intracellular protein recruitment.

引用

收藏

页码：281 / 286

页数：6

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