Mayaro Fever in the City of Manaus, Brazil, 2007-2008

被引：97

作者：

Gomes Mourao, Maria Paula ^{[1
,2
,3
]}

Bastos, Michele de Souza ^{[1
,2
]}

de Figueiredo, Regina Pinto ^{[1
]}

Lima Gimaque, Joao Bosco ^{[1
,2
]}

Galusso, Elizabeth dos Santos ^{[1
]}

Kramer, Valeria Munique ^{[4
]}

Costa de Oliveira, Cintia Mara ^{[1
]}

Naveca, Felipe Gomes ^{[5
]}

Moraes Figueiredo, Luiz Tadeu ^{[6
]}

机构：

[1] Fundacao Med Trop Dr Heitor Viera Dourado FMT HVD, Dept Virol, BR-69040000 Manaus, Amazonas, Brazil

[2] Univ Estado Amazonas, Trop Med Postgrad Program, Manaus, Amazonas, Brazil

[3] Univ Nilton Lins, Unictr, Manaus, Amazonas, Brazil

[4] Univ Fed Amazonas UFAM, Fac Pharm, Manaus, Amazonas, Brazil

[5] Fundacao Oswaldo Cruz FIOCRUZ, Inst Pesquisa Leonidas & Maria Deane ILDM, Manaus, Amazonas, Brazil

[6] Fac Med Ribeirao Preto FMRP USP, Ctr Pesquisas Virol, Sao Paulo, Brazil

来源：

VECTOR-BORNE AND ZOONOTIC DISEASES | 2012年 / 12卷 / 01期

关键词：

Alphavirus; Arbovirus; Brazilian Amazon; Mayaro fever; HUMAN DISEASE AGENT; VIRUS-DISEASE; OUTBREAK; BELTERRA; INFECTION;

D O I：

10.1089/vbz.2011.0669

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Mayaro Alphavirus is an arbovirus that causes outbreaks of acute febrile illness in the Amazon region of South America. We show here the cases of Mayaro fever that occurred in 2007-2008, in Manaus, a large city and capital of the Amazonas State, in Western Brazilian Amazon. IgM antibodies to Mayaro virus (MAYV) were detected by an enzyme immunoassay using infected cell cultures as antigen in the sera of 33 patients from both genera and 6-65 years old. MAYV genome was also detected by RT-PCR in the blood of 1/33 of these patients. The patients presented mainly with headache, arthralgia, myalgia, ocular pain, and rash. These cases of Mayaro fever are likely to represent the tip of an iceberg, and probably a much greater number of cases occurred in Manaus in the study period.

引用

页码：42 / 46

页数：5

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