Hitting old targets better and identifying new targets

被引：10

作者：

Chen, Yu ^{[1
,2
]}

Scher, Howard I. ^{[1
,2
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, New York, NY 10065 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10065 USA

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2012年 / 9卷 / 02期

关键词：

PROSTATE-CANCER; MORTALITY;

D O I：

10.1038/nrclinonc.2011.213

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Options to treat late-stage castration-resistant prostate cancer continued to increase in 2011, as three agents with different mechanisms of action prolonged life and a fourth reduced the morbidity of skeletal metastases. These outcomes contrasted with the heightened controversy generated by the recommendation against PSA screening and other early detection strategies. Chen, Y. & Scher, H. I. Nat. Rev. Clin. Oncol. 9, 70-72 (2012); published online 10 January 2012; doi:10.1038/nrclinonc.2011.213

引用

页码：70 / 72

页数：3

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