Hydrogel stamping of arrays of supported lipid bilayers with various lipid compositions for the screening of drug-membrane and protein-membrane interactions

被引：64

作者：

Majd, S

Mayer, M

机构：

[1] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 41期

关键词：

hydrogel; lipids; membranes; micropatterning;

D O I：

10.1002/anie.200502189

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Stamping on fat: Agarose gel stamps were used to create ≥100 membrane arrays (see picture) by using only picomolar amounts of lipids. This constitutes a rapid and straightforward method for the fabrication of functional membrane arrays with a variety of lipid compositions which can be used for screening assays, for example, for drug-membrane interactions. (Figure Presented) © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：6697 / 6700

页数：4

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