Human puromycin-sensitive aminopeptidase:: cloning of 3′ UTR, evidence for a polymorphism at aa 140 and refined chromosomal localization to 17q21

被引:6
作者
Bauer, WO
Nanda, I
Beck, G
Schmid, M
Jakob, F
机构
[1] Univ Wurzburg, Med Poliklin, Dept Metab Endocrinol & Mol Med, D-97070 Wurzburg, Germany
[2] Univ Wurzburg, Dept Human Genet, D-97070 Wurzburg, Germany
来源
CYTOGENETICS AND CELL GENETICS | 2001年 / 92卷 / 3-4期
关键词
D O I
10.1159/000056907
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Puromycin-sensitive aminopeptidase is a predominantly cytoplasmatic zinc-dependent exopeptidase. Its physiological function is not known to date. Here we report data on tissue distribution, a polymorphism within the coding region and the complete 3' UTR. The gene (NPEPPS alias PSA) was physically mapped to chromosome 17q21.2 --> q21.32 using fluorescence in situ hybridization. Copyright (C) 2001 S. Karger AG, Basel.
引用
收藏
页码:221 / 224
页数:4
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