Kinetics for the acid-catalyzed hydrolysis of purine and cytosine 2′-deoxy-4′-thionucleosides

被引：15

作者：

Elzagheid, MI

Oivanen, M ^{[1
]}

Walker, RT

Secrist, JA

机构：

[1] Univ Turku, Dept Chem, FIN-20014 Turku, Finland

[2] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

[3] So Res Inst, Birmingham, AL 35255 USA

来源：

NUCLEOSIDES & NUCLEOTIDES | 1999年 / 18卷 / 02期

关键词：

D O I：

10.1080/15257779908043065

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hydrolysis of adenine, guanine and cytosine 2'-deoxy-4'-thionucleosides in aqueous acid has been followed by HPLC. Stability of the compounds and mechanisms of hydrolysis are discussed in comparison with those of the corresponding native 2'-deoxynucleosides.

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页码：181 / 186

页数：6

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