Mass spectrometric analysis of illicit drugs in wastewater and surface water

被引：108

作者：

Castiglioni, Sara ^{[1
]}

Zuccato, Ettore ^{[1
]}

Chiabrando, Chiara ^{[1
]}

Fanelli, Roberto ^{[1
]}

Bagnati, Renzo ^{[1
]}

机构：

[1] Mario Negri Inst Pharmacol Res, Dept Environm Hlth Sci, I-20156 Milan, Italy

来源：

MASS SPECTROMETRY REVIEWS | 2008年 / 27卷 / 04期

关键词：

mass spectrometry; tandem mass spectrometry; liquid chromatography; illicit drugs residues; wastewater; surface water;

D O I：

10.1002/mas.20168

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Residues of illicit drugs have been recently found in urban wastewater and surface water. Their levels reflect the amount of drugs collectively excreted by consumers and can therefore be used to estimate drug abuse. An overview of the most widely used illicit drugs and of the analytical methods used for their detection in wastewater and surface water is presented here. Solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry are the techniques that have been used for these investigations. Instrumental conditions and fragmentation patterns of illicit drugs and their metabolites are described.

引用

页码：378 / 394

页数：17

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