The inositol triphosphate receptor family

被引:114
作者
Joseph, SK
机构
[1] Dept. of Pathology and Cell Biology, Thomas Jefferson University, School of Medicine, Philadelphia, PA 19107
关键词
Ca2+ mobilization; IP3; receptor; Ca2+ channels;
D O I
10.1016/0898-6568(95)02012-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Specific receptors on intracellular membranes mediate the Ca2+ mobilization induced by the second messenger molecule D-myo-inositol 1,4,5-triphosphate (IP3). Most cell types appear to contain multiple receptor isoforms. The review summarizes recent progress on IP3 receptor biology with a particular emphasis on distinctive structural and regulatory features of the individual isoforms.
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页码:1 / 7
页数:7
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