Changes of minimal erythema dose after water and salt water baths

被引:22
作者
Gambichler, T [1 ]
Schropl, F [1 ]
机构
[1] Klin Bad Sulza, Dept Dermatol, Bad Sulza, Germany
关键词
minimal erythema dose; photosensitization; phototherapy; balneophototherapy; salt water baths;
D O I
10.1111/j.1600-0781.1998.tb00022.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Knowledge about the influence of salt water baths on UV irradiation, especially balneophototherapy, is incomplete. The aim of this study was to investigate the influence of various concentrated salt solutions on the minimal erythema dose (MED). We determined the MEDdry (UVB) in 24 healthy, previously UV unexposed subjects on the inner forearm. Subjects were divided randomly into two groups of 12. Subsequently, the MEDdry was assessed on each forearm after 30 min tap water or 5% salt water bath (group A), respectively, or after 30 min 10% or 20% salt water bath (group B)? respectively. Compared with the MEDdry a significantly decreased MEDdry was observed after all exposures (group A double right arrow F= 18.94; P<0.001; group B double right arrow F=11.73; P<0.006). A maximal relative decrease in MEDdry of about 51.4% was observed after the 10% salt water bath. The 5% salt solution caused a modest relative decrease in MEDdry of 23.4%. We observed a markedly increased photosensitivity to UVB after all exposures, without a linear correlation between the MED and the salt water concentration. A determination of MED during balneophototherapy should be carried out after bathing in order to reduce the cumulative UV dose and to prevent acute photodamage.
引用
收藏
页码:109 / 111
页数:3
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