Studies of reservoir hosts for Marburg virus

被引：186

作者：

Swanepoel, Robert ^{[1
]}

Smit, Sheilagh B.

Rollin, Pierre E.

Formenty, Pierre

Leman, Patricia A.

Kemp, Alan

Burt, Felicity J.

Grobbelaar, Antoinette A.

Croft, Janice

Bausch, Daniel G.

Zeller, Herve

Leirs, Herwig

Braack, L. E. O.

Libande, Modeste L.

Zaki, Sherif

Nichol, Stuart T.

Kslazek, Thomas G.

Paweska, Janusz T.

机构：

[1] Natl Inst Communicable Dis, Private Bag X4, ZA-2131 Johannesburg, South Africa

[2] Ctr Dis Control & Prevent, Atlanta, GA USA

[3] WHO, CH-1211 Geneva, Switzerland

[4] Univ Free State, Bloemfontein, South Africa

[5] Tulane Sch Publ Hlth & Trop Med, New Orleans, LA USA

[6] Inst Pasteur, Lyon, France

[7] Univ Antwerp, B-2020 Antwerp, Belgium

[8] Univ Aarhus, Lyngby, Denmark

[9] Conservat Int, Cape Town, South Africa

[10] Dept Hlth, Watsa, DEM REP CONGO

来源：

EMERGING INFECTIOUS DISEASES | 2007年 / 13卷 / 12期

关键词：

D O I：

10.3201/eid1312.071115

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.

引用

页码：1847 / 1851

页数：5

共 16 条

[1]

Arata A., 1977, EBOLA VIRUS HAEMORRH, P191

[2] Marburg hemorrhagic fever associated with multiple genetic lineages of virus [J].

Bausch, Daniel G. ;

Nichol, Stuart T. ;

Muyembe-Tamfum, Jean Jacques ;

Borchert, Matthias ;

Rollin, Pierre E. ;

Sleurs, Hilde ;

Campbell, Patricia ;

Tshioko, Florimund K. ;

Roth, Catherine ;

Colebunders, Robert ;

Pirard, Patricia ;

Mardel, Simon ;

Olinda, Loku A. ;

Zeller, Herve ;

Tshomba, Antoine ;

Kulidri, Amayo ;

Libande, Modeste L. ;

Mulangu, Sabue ;

Formenty, Pierre ;

Grein, Thomas ;

Leirs, Herwig ;

Braack, Leo ;

Ksiazek, Tom ;

Zaki, Sherif ;

Bowen, Michael D. ;

Smit, Sheilagh B. ;

Leman, Patricia A. ;

Burt, Felicity J. ;

Kemp, Alan ;

Swanepoel, Robert .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (09) :909-919

[3] Bats: Important reservoir hosts of emerging viruses [J].

Calisher, Charles H. ;

Childs, James E. ;

Field, Hume E. ;

Holmes, Kathryn V. ;

Schountz, Tony .

CLINICAL MICROBIOLOGY REVIEWS, 2006, 19 (03) :531-+

[4] EPIDEMIOLOGIC INVESTIGATION OF MARBURG VIRUS-DISEASE, SOUTHERN-AFRICA, 1975 [J].

CONRAD, JL ;

ISAACSON, M ;

SMITH, EB ;

WULFF, H ;

CREES, M ;

GELDENHUYS, P ;

JOHNSTON, J .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1978, 27 (06) :1210-1215

[5] Ebola virus outbreak among wild chimpanzees living in a rain forest of Cote d'Ivoire [J].

Formenty, P ;

Boesch, C ;

Wyers, M ;

Steiner, C ;

Donati, F ;

Dind, F ;

Walker, F ;

Le Guenno, B .

JOURNAL OF INFECTIOUS DISEASES, 1999, 179 :S120-S126

[6]

HYATT A. D., 2004, ECOHEALTH, V1, P25, DOI DOI 10.1007/S10393-004-0017-6

[7]

Johnson ED, 1996, ARCH VIROL, P101

[8]

KINGDON J, 1984, E AFRICAN MAMMALS A, V2

[9] MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment [J].

Kumar, S ;

Tamura, K ;

Nei, M .

BRIEFINGS IN BIOINFORMATICS, 2004, 5 (02) :150-163

[10] Fruit bats as reservoirs of Ebola virus [J].

Leroy, EM ;

Kumulungui, B ;

Pourrut, X ;

Rouquet, P ;

Hassanin, A ;

Yaba, P ;

Délicat, A ;

Paweska, JT ;

Gonzalez, JP ;

Swanepoel, R .

NATURE, 2005, 438 (7068) :575-576

← 1 2 →