The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa

被引：306

作者：

Al-Ghamdi, MS ^{[1
]}

机构：

[1] King Faisal Univ, Coll Med, Dept Pharmacol, Dammam 31451, Saudi Arabia

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 76卷 / 01期

关键词：

N; sativa; anti-inflammatory; analgesic; folk medicine;

D O I：

10.1016/S0378-8741(01)00216-1

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The aqueous extract of Nigella sativa (N. sativa) was investigated for anti-inflammatory, analgesic and antipyretic activities in animal models. The extract has an anti-inflammatory effect demonstrated by its inhibitory effects on Carrageenan induced paw edema. It also produced significant increase in the hot plate reaction time in mice indicating analgesic effect. However, N. sativa crude suspension had no effect on yeast induced pyrexia. This study therefore, supports its use in folk medicine both as analgesic and anti-inflammatory agent and calls for further investigations to elucidate its mechanism of action. (C) 2001 Elsevier Science ireland Ltd. All rights reserved.

引用

页码：45 / 48

页数：4

共 18 条

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