Bacterial virulence effectors and their activities

被引:69
作者
Hann, Dagmar R. [2 ]
Gimenez-Ibanez, Selena [3 ]
Rathjen, John P. [1 ]
机构
[1] Australian Natl Univ, Res Sch Biol, Canberra, ACT 0200, Australia
[2] Univ Basel, Inst Bot, Sect Plant Physiol, CH-4056 Basel, Switzerland
[3] CSIC, Ctr Nacl Biotecnol, Dept Genet Mol Plantas, E-28049 Madrid, Spain
基金
澳大利亚研究理事会; 美国国家科学基金会;
关键词
E3 UBIQUITIN LIGASE; PV. TOMATO DC3000; PSEUDOMONAS-SYRINGAE; III EFFECTOR; INNATE IMMUNITY; PLANT IMMUNITY; ARABIDOPSIS RIN4; GENOME SEQUENCE; NICOTIANA-BENTHAMIANA; DISEASE RESISTANCE;
D O I
10.1016/j.pbi.2010.04.003
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The major virulence strategy for plant pathogenic bacteria is deployment of effector molecules within the host cytoplasm. Each bacterial strain possesses a set of 20-30 effectors which have overlapping activities, are functionally interchangeable, and diverge in composition between strains. Effectors target host molecules to suppress immunity. Two main strategies are apparent. Effectors that target host proteins seem to attack conserved structural domains but otherwise lack specificity. On the other hand, those that influence host gene transcription directly do so with extreme specificity. In both cases, examples are known where the host has exploited effector-target affinities to establish immune recognition of effectors. The molecular activity of each effector links virulence and immune outcomes.
引用
收藏
页码:388 / 393
页数:6
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