Yersinia HPI in septicemic Escherichia coli strains isolated from diverse hosts

被引:49
作者
Gophna, U
Oelschlaeger, TA
Hacker, J
Ron, EZ [1 ]
机构
[1] Tel Aviv Univ, George S Wise Fac Life Sci, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel
[2] Inst Mol Infekt Biol, D-97070 Wurzburg, Germany
关键词
high pathogenity island (HPI); Yersinia; Escherichia coli;
D O I
10.1111/j.1574-6968.2001.tb10540.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
High pathogenicity islands (HPIs), first identified in various Yersinia species, encode an iron uptake system. We have studied the occurrence of HPIs in septicemic strains of Escherichia coli isolated from a variety of hosts. The results presented in this communication indicate that most septicemic strains tested contained HPI sequences even though they already have the aerobactin encoding genes. We have also observed two types of HPI deletions, suggesting genetic instability of this element. Notable exceptions are several strains isolated from septicemia in sheep that lacked both iron acquisition systems. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:57 / 60
页数:4
相关论文
共 13 条
[1]   Virulence patterns from septicemic Escherichia coli O78 strains [J].
Babai, R ;
BlumOehler, G ;
Stern, BE ;
Hacker, J ;
Ron, EZ .
FEMS MICROBIOLOGY LETTERS, 1997, 149 (01) :99-105
[2]   The Yersinia high-pathogenicity island is present in different members of the family Enterobacteriaceae [J].
Bach, S ;
de Almeida, A ;
Carniel, E .
FEMS MICROBIOLOGY LETTERS, 2000, 183 (02) :289-294
[3]   EXCISION OF LARGE DNA REGIONS TERMED PATHOGENICITY ISLANDS FROM TRANSFER-RNA-SPECIFIC LOCI IN THE CHROMOSOME OF AN ESCHERICHIA-COLI WILD-TYPE PATHOGEN [J].
BLUM, G ;
OTT, M ;
LISCHEWSKI, A ;
RITTER, A ;
IMRICH, H ;
TSCHAPE, H ;
HACKER, J .
INFECTION AND IMMUNITY, 1994, 62 (02) :606-614
[4]  
CHERIFI A, 1994, J CLIN MICROBIOL, V32, P1197
[6]   A genomic island, termed high-pathogenicity island, is present in certain non-O157 shiga toxin-producing Escherichia coli clonal lineages [J].
Karch, H ;
Schubert, S ;
Zhang, D ;
Zhang, W ;
Schmidt, H ;
Ölschlager, T ;
Hacker, J .
INFECTION AND IMMUNITY, 1999, 67 (11) :5994-6001
[7]   PRESENCE AND EXPRESSION OF AEROBACTIN GENES IN VIRULENT AVIAN STRAINS OF ESCHERICHIA-COLI [J].
LAFONT, JP ;
DHO, M ;
DHAUTEVILLE, HM ;
BREE, A ;
SANSONETTI, PJ .
INFECTION AND IMMUNITY, 1987, 55 (01) :193-197
[8]   Lack of a role for iron in the Lyme disease pathogen [J].
Posey, JE ;
Gherardini, FC .
SCIENCE, 2000, 288 (5471) :1651-1653
[9]  
ROGERS HJ, 1973, J INFECT IMMUN, V7, P438
[10]   DNA SEQUENCING WITH CHAIN-TERMINATING INHIBITORS [J].
SANGER, F ;
NICKLEN, S ;
COULSON, AR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5463-5467