Rapid progression of hepatocellular carcinoma after transcatheter arterial chemoembolization and percutaneous radiofrequency ablation in the primary tumour region

被引:84
作者
Seki, T [1 ]
Tamai, T [1 ]
Ikeda, K [1 ]
Imamura, M [1 ]
Nishimura, A [1 ]
Yamashiki, N [1 ]
Nakagawa, T [1 ]
Inoue, K [1 ]
机构
[1] Kansai Med Univ, Dept Internal Med 3, Osaka 5708507, Japan
关键词
hepatocellular carcinoma; percutaneous radiofrequency ablation; rapid progression; transcatheter arterial chemoembolization;
D O I
10.1097/00042737-200103000-00014
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
We report one patient who showed rapid progression of hepatocellular carcinoma (HCC) after undergoing transcatheter arterial chemoembolization (TACE) and percutaneous radiofrequency ablation (PRFA) for a small HCC measuring 2.5 cm in diameter. Enhanced magnetic resonance imaging (MRI) following treatment showed complete tumour necrosis and did not reveal the presence of a tumour around the treated area. Furthermore, the serum alpha-fetoprotein (AFP) level decreased at the completion of therapy, However, the HCC advanced in a very short time. Numerous tumours around the treated area were observed on enhanced computed tomography (CT) 50 days after PRFA. It is strongly suspected that the tumour was disseminated through the portal system because of the presence pattern of tumours. We believe this to be the first case illustrating a hepatic cancer that progressed rapidly following TACE and PRFA. Eur J Gastroenterol Hepatol 13:291-294 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:291 / 294
页数:4
相关论文
共 16 条
  • [1] ADACHI E, 1993, CANCER, V72, P3593, DOI 10.1002/1097-0142(19931215)72:12<3593::AID-CNCR2820721208>3.0.CO
  • [2] 2-T
  • [3] TUMOR NECROSIS CAN FACILITATE THE APPEARANCE OF METASTASES
    BONFIL, RD
    BUSTUOABAD, OD
    RUGGIERO, RA
    MEISS, RP
    PASQUALINI, CD
    [J]. CLINICAL & EXPERIMENTAL METASTASIS, 1988, 6 (02) : 121 - 129
  • [4] Percutaneous radiofrequency thermal ablation combined with transcatheter arterial embolization in the treatment of large hepatocellular carcinoma
    Buscarini, L
    Buscarini, E
    Di Stasi, M
    Quaretti, P
    Zangrandi, A
    [J]. ULTRASCHALL IN DER MEDIZIN, 1999, 20 (02): : 47 - 53
  • [5] Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies - Results in 123 patients
    Curley, SA
    Izzo, F
    Delrio, P
    Ellis, LM
    Granchi, J
    Vallone, P
    Fiore, F
    Pignata, S
    Daniele, B
    Cremona, F
    [J]. ANNALS OF SURGERY, 1999, 230 (01) : 1 - 8
  • [6] Ablation of liver tumors using percutaneous RF therapy
    Goldberg, SN
    Gazelle, GS
    Solbiati, L
    Livraghi, T
    Tanabe, KK
    Hahn, PF
    Mueller, PR
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 1998, 170 (04) : 1023 - 1028
  • [7] KATAGIRI S, 1999, ACTA HEPATOL JPN, V40, P568
  • [8] KURODA C, 1991, CANCER, V67, P81, DOI 10.1002/1097-0142(19910101)67:1<81::AID-CNCR2820670116>3.0.CO
  • [9] 2-H
  • [10] Small hepatocellular carcinoma: Treatment with radio-frequency ablation versus ethanol injection
    Livraghi, T
    Goldberg, SN
    Lazzaroni, S
    Meloni, F
    Solbiati, L
    Gazelle, GS
    [J]. RADIOLOGY, 1999, 210 (03) : 655 - 661