Electrophilic alpha-p-tolylhydrazonylation of tert-butyl alkanoates and tertiary alkanamides with tert-butyl p-tolylazo sulfide

被引：9

作者：

DellErba, C ^{[1
]}

Novi, M ^{[1
]}

Petrillo, G ^{[1
]}

Tavani, C ^{[1
]}

机构：

[1] CNR,CTR STUDIO CHIM COMPOSTI CICLOALIFAT & AROMAT,DIPARTIMENTO CHIM & CHIM IND,I-16146 GENOA,ITALY

来源：

TETRAHEDRON | 1996年 / 52卷 / 16期

关键词：

D O I：

10.1016/0040-4020(96)00219-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of the enolates of tert-butyl alkanoates 2 and N,N-dialkylalkanamides 3 with tert-butyl p-tolylazo sulfide 1 in THF furnish good yields of the corresponding alpha-p-tolylhydrazonylated esters 4 and amides 5. Results are reported showing the possible transformation of 4 and 5 into the N-methylated derivatives 8 and 9 and the subsequent deblocking of the protected carbonyl function to the corresponding 2-oxoalkanoates 10 and 2-oxoalkanamides 11. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5889 / 5898

页数：10

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