Measurement of nasal nitric oxide

被引:11
作者
Corbelli, Regula
Hammer, Juerg
机构
[1] Univ Childrens Hosp, CH-1211 Geneva, Switzerland
[2] Univ Childrens Hosp, Div Intens Care & Pulm, Basel, Switzerland
关键词
nasal nitric oxide; primary ciliary dyskinesia;
D O I
10.1016/j.prrv.2007.07.007
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Nasal nitric oxide (nNO) is produced in high quantity in the upper airways. It is thought to be involved in host defence functions and regulation of mucociliary function, and to serve as a biochemical airborne transmitter. The measurement of nNO is easy and non-invasive. It has evolved as a screening test to exclude primary ciliary dyskinesia (PCD) in patients with suggestive symptoms, because nNO is extremely low in this condition. Nasal NO is also altered in other nasal, sinus and pulmonary pathologies, but is without diagnostic value outside of PCD. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:269 / 272
页数:4
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