hypersomnolence;
Kleine-Levin syndrome;
hypothalamus;
precocious puberty;
lead poisoning;
D O I:
10.1097/00004583-199608000-00016
中图分类号:
B844 [发展心理学(人类心理学)];
学科分类号:
040202 ;
摘要:
The limited literature on hypersomnolence suggests that it is a poorly defined symptom associated with a spectrum of disorders from monosymptomatic hypersomnolence to the Kleine-Levin syndrome. These disorders often herald an organic central nervous system syndrome. Recent evidence suggests a frequent association between these disorders and hypothalamic dysfunction, which itself may be caused by a variety of factors. This case study of a patient with persistent hypersomnolence, hypothalamic dysfunction (in the form of precocious puberty), pica, and chronic lead intoxication strengthens the association between hypersomnolence and hypothalamic dysfunction and suggests a heretofore unreported cause of hypothalamic dysfunction in humans.