Analysis of recombination in Campylobacter jejuni from MLST population data

被引：46

作者：

Fearnbead, P ^{[1
]}

Smith, NGC

Barrigas, M

Fox, A

French, N

机构：

[1] Univ Lancaster, Dept Math & Stat, Lancaster LA1 4YF, England

[2] Manchester Royal Infirm, Manchester Med Microbiol Partnership, Hlth Protect Agcy NW, Manchester M13 9WL, Lancs, England

[3] Massey Univ, Inst Vet Anim & Biomed Sci, Palmerston North, New Zealand

来源：

JOURNAL OF MOLECULAR EVOLUTION | 2005年 / 61卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

bacteria; Campylobacter; Helicobacter; MLST; recombination rate; recombination tract length;

D O I：

10.1007/s00239-004-0316-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km(2) study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225-750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.

引用

页码：333 / 340

页数：8

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