European bat lyssavirus in Scottish bats

被引：57

作者：

Brookes, SM

Aegerter, JN

Smith, GC

Healy, DM

Jolliffe, TA

Swift, SM

Mackie, IJ

Pritchard, S

Racey, PA

Moore, NP

Fooks, AR ^{[1
]}

机构：

[1] WHO, Rabies Res & Diagnost Grp, Vet Labs Agcy Weybridge, Collaborating Ctr Characterisat Rabies & Rabies R, Surrey KT15 3NB, England

[2] Cent Sci Lab, York, N Yorkshire, England

[3] Univ Aberdeen, Aberdeen, Scotland

来源：

EMERGING INFECTIOUS DISEASES | 2005年 / 11卷 / 04期

关键词：

D O I：

10.3201/eid1104.040920

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report the first seroprevalence study of the occurrence of specific antibodies to European bat lyssavirus type 2 (EBLV-2) in Daubenton's bats. Bats were captured from 19 sites across eastern and southern Scotland. Samples from 198 Daubenton's bats, 20 Natterer's bats, and 6 Pipistrelle's bats were tested for EBLV-2. Blood samples (N = 94) were subjected to a modified fluorescent antibody virus neutralization test to determine antibody titer. From 0.05% to 3.8% (95% confidence interval) of Daubenton's bats were seropositive. Antibodies to EBLV-2 were not detected in the 2 other species tested. Mouth swabs (N = 218) were obtained, and RNA was extracted for a reverse transcription-polymerase chain reaction (RTPCR). The RT-PCR included pan lyssavirus-primers (N gene) and internal PCR control primers for ribosomal RNA. EBLV-2 RNA was not detected in any of the saliva samples tested, and live virus was not detected in virus isolation tests.

引用

页码：572 / 578

页数：7

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