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Neutrophil-Kupffer-cell interaction in host defenses to systemic infections

被引：52
作者：
Gregory, SH
Wing, EJ
机构：
[1] Univ Pittsburgh, Sch Med, Dept Med, Pittsburgh, PA 15213 USA
[2] Brown Univ, Rhode Isl Hosp, Sch Med, Dept Med, Providence, RI 02903 USA
来源：
IMMUNOLOGY TODAY | 1998年 / 19卷 / 11期
关键词：
D O I：
10.1016/S0167-5699(98)01319-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Most relevant textbooks characterize phagocytosis by Kupffer cells as the principal mechanism for clearing bacterial pathogens from the bloodstream and eliminating them from the liver. Here, Stephen Gregory and Edward Wing discuss recent evidence indicating that the actual mechanism is far more complicated, dependent upon the complex interaction of Kupffer cells with neutrophils that immigrate into the liver following infection.
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页码：507 / 510
页数：4
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