Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

被引：17

作者：

Albada, H. Bauke ^{[1
]}

Soulimani, Fouad ^{[2
]}

Weckhuysen, Bert M. ^{[2
]}

Liskamp, Rob M. J. ^{[1
]}

机构：

[1] Univ Utrecht, Fac Sci, Utrecht Inst Pharmaceut Sci, NL-3508 TB Utrecht, Netherlands

[2] Univ Utrecht, Fac Sci, Dept Chem, Inorgan Chem & Catalysis Grp, NL-3584 CA Utrecht, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 46期

关键词：

D O I：

10.1039/b709400k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the use of triazacyclophane (TAC)-scaffolded amino acids as a structural mimic for 3-histidine metal-binding sites in metalloproteins, especially for the mimicry of type-3 copper binding sites as are present in hemocyanin, tyrosinase and catechol oxidase.

引用

页码：4895 / 4897

页数：3

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