Synthesis of optically active alpha-phenylpyridylmethanols by immobilized cell cultures of Catharanthus roseus

被引:22
作者
Takemoto, M [1 ]
Achiwa, K [1 ]
Stoynov, N [1 ]
Chen, D [1 ]
Kutney, JP [1 ]
机构
[1] UNIV BRITISH COLUMBIA, DEPT CHEM, VANCOUVER, BC V6T 1Y6, CANADA
关键词
Catharanthus roseus; Apocynaceae; Nicotiana tabacum; Solanaceae; biotransformation; reduction; hydrolysis; benzoylpyridine; chiral alpha-phenylpynidylmethanol;
D O I
10.1016/0031-9422(95)00915-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have synthesized optically active alpha-phenylpyridylmethanols by reduction or hydrolysis with calcium alginate immobilized cells of Catharanthus roseus.
引用
收藏
页码:423 / 426
页数:4
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