Non heart-beating donors in england

被引:14
作者
Chaib, Eleazar [1 ]
机构
[1] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg, Oxford OX3 9DU, England
关键词
transplantation; liver; kidney; donors;
D O I
10.1590/S1807-59322008000100020
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
When transplantation started all organs were retrieved from patients immediately after cardio-respiratory arrest, i.e. from non-heart-beating donors. After the recognition that death resulted from irreversible damage to the brainstem, organ retrieval rapidly switched to patients certified dead after brainstem testing. These heart-beating-donors have become the principal source of organs for transplantation for the last 30 years. The number of heart-beating-donors are declining and this is likely to continue, therefore cadaveric organs from non-heart-beating donor offers a large potential of resources for organ transplantation. The aim of this study is to examine clinical outcomes of non-heart-beating donors in the past 10 years in the UK as an way of decreasing pressure in the huge waiting list for organs transplantation.
引用
收藏
页码:121 / 134
页数:14
相关论文
共 116 条
[1]   Liver transplantation from controlled non-heartbeating donors: An increased incidence of biliary complications [J].
Abt, P ;
Crawford, M ;
Desai, N ;
Markmann, J ;
Olthoff, K ;
Shaked, A .
TRANSPLANTATION, 2003, 75 (10) :1659-1663
[2]   Survival following liver transplantation from non-heart-beating donors [J].
Abt, PL ;
Desai, NM ;
Crawford, MD ;
Forman, LM ;
Markmann, JW ;
Olthoff, KM ;
Markmann, JF .
ANNALS OF SURGERY, 2004, 239 (01) :87-92
[3]   Factors influencing short- and long-term survival of kidneys transplanted from non-heart-beating donors [J].
Alvarez, J ;
del Barrio, R ;
Martin, M ;
Rodriguez, G ;
Blesa, AL ;
Ramos, J ;
Nieto, M ;
Martin-Santos, F .
TRANSPLANTATION PROCEEDINGS, 1997, 29 (08) :3490-3490
[4]  
ALVAREZRODRIGUEZ J, 1995, TRANSPLANT P, V27, P2903
[5]  
[Anonymous], 1968, JAMA, V205, P337
[6]   GLUTATHIONE TRANSFERASE IN THE URINE - A MARKER FOR POST-TRANSPLANT TUBULAR LESIONS [J].
BACKMAN, L ;
APPELKVIST, EL ;
RINGDEN, O ;
DALLNER, G .
KIDNEY INTERNATIONAL, 1988, 33 (02) :571-577
[7]   Comparison of renal allograft fibrosis after transplantation from heart-beating and non-heart-beating donors [J].
Bains, JC ;
Sandford, RM ;
Brook, NR ;
Hosgood, SA ;
Lewis, GRR ;
Nicholson, ML .
BRITISH JOURNAL OF SURGERY, 2005, 92 (01) :113-118
[8]  
Balupuri S, 2000, TRANSPLANTATION, V69, P842
[9]  
Balupuri S, 2000, Transpl Int, V13 Suppl 1, pS255, DOI 10.1007/s001470050336
[10]   Machine perfusion and viability assessment of non-heart-beating donor kidneys - A single-centre result [J].
Balupuri, S ;
Mantle, D ;
Mohamed, M ;
Shenton, B ;
Gok, M ;
Soomro, N ;
Manas, DM ;
Kirby, J ;
Talbot, D .
TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) :1119-1120